Program Content
Core courses Exemplar content
Translational Medicine: introduction and definition

This course provides background and introduction to the emerging discipline of Translational Medicine and the increasingly important role it will play in biomedical research and the biopharmaceutical industry.

 

TM in action: drivers and barriers.
Inter-relationships from ‘bench to bedside’

Mechanisms and models of disease

Translational Medicine provides an integrated and interdisciplinary approach for the improved understanding and treatment of disease.  This course will highlight the increasing requirement to understand and define disease at a multi-system level (molecules > populations) to enable more sophisticated analysis of the origin and pathogenesis of disease processes.

 

Fundamentals of disease mechanisms
In vitro vs in vivo disease models
Stem cell & gene therapies

Targeting and measuring disease

This course describes the spectrum of clinical, scientific and societal metrics and measurements required in Translational Medicine research for the identification and definition of disease systems at various levels.

 

Post genomic technologies
Imaging technologies
Systemic measurements
Biomarkers

Challenges of drug development: past and future

This key course explores current and emerging challenges facing the biopharmaceutical industry and the major role Translational Medicine will play in future drug development strategies.

 

Conventional drug discovery
Translational approaches to drug discovery
PharmacogenomicsBiological

Translational strategies, policy and regulation, and stakeholder engagement

This course will complement others in the programme which are dealing with the scientific and medical contexts and will focus on strategic, policy and regulatory aspects. It will consider the requirements of a wide range of medical advances (from drugs to tissue engineering) in terms of innovative strategic approaches to deliver advances to patients, and the contrasting requirements for effective translation in commercial companies and health services.

 


Ethics of tissue banking
Legal frameworks
Patient group interface
IP issues

Interdisciplinary integrative research skills

The Certificate will provide participants with an in depth understanding of the rationale and impact of Translational Medicine and appreciation of its increasingly important role to medical research, the drug development industry and regulatory sectors.  The multidisciplinary, integrative and interactive nature of Translational Medicine will be highlighted and understanding of its relevance and impact to scientific, medical and societal sectors will be gained. 

 

Interdisciplinary research teams
Medical bioinformatics & systems analysis
Clinical trial evaluation
Translational Medicine case studies