Serono Symposia International Foundation adheres to guidelines of the European Accreditation Council for Continuing Medical Education (EACCME) and all other professional organizations, as applicable, which state that programs awarding continuing education credits must be balanced, independent, objective, and scientifically rigorous. Investigative and other uses for pharmaceutical agents, medical devices, and other products (other than those uses indicated in approved product labeling/package insert for the product) may be presented in the program (which may reflect clinical experience, the professional literature or other clinical sources known to the presenter). We ask all presenters to provide participants with information about relationships with pharmaceutical or medical equipment companies that may have relevance to their lectures. This policy is not intended to exclude faculty who have relationships with such companies; it is only intended to inform participants of any potential conflicts so participants may form their own judgments, based on full disclosure of the facts. Further, all opinions and recommendations presented during the program and all program-related materials neither imply an endorsement, nor a recommendation, on the part of Serono Symposia International Foundation. All presentations solely represent the independent views of the presenters/authors.

The following faculty indicated no significant commercial relationships and/or discussions of investigational or non- EMEA/FDA approved (off-label) uses of drugs:

Oscar Fernández
Gianvito Martino
Jaume Sastre-Garriga
Helen Tremlett

The following faculty provided information regarding significant commercial relationships and/or discussions of investigational or non- EMEA/FDA approved (off-label) uses of drugs:

Giancarlo Comi - Declared receipt of honoraria or consultation fees from Bayer Schering, Teva, Merck Serono and Biogen Dompè.

Christian Confavreux - Declared receipt of grants and contracts from Teva, Sanofi-Aventis, Biogen Idec, Merck Serono and Bayer Schering, and honoraria or consultation fees from Sanofi-Aventis and Genzyme. Declared also to be a member of Sanofi-Aventis and Genzyme advisory boards.

Douglas Goodin - Declared receipt of grants and contracts from Teva, Bayer, Merck Serono and Biogen Idec, and honoraria or consultation fees from Teva, Bayer and Merck Serono.

Xavier Montalban - Declared receipt of honoraria or consultation fees from Bayer Schering, Biogen Idec, Teva and Sanofi-Aventis.

Peter Rieckmann - Declared receipt of honoraria or consultation fees from Merck Serono, Bayer, Teva and Biogen Idec. Declared also to be a member of Bayer and Merck Serono advisory boards.

Magnhild Sandberg-Wollheim - Declared receipt of contracts from Merck Serono for DSMB work and honoraria or consultation fees from Merck Serono, Biogen Idec, Sanofi-Aventis and Bayer Healthcare. Declared also to be member of the Active Biotech Research Board of Directors.

Per Soelberg Sørensen - Declared receipt of honoraria for lecturing, advisory councils and trial steering committees or travel expenses for attending meetings, from Biogen Idec, Schering, Merck Serono, Teva, Baxter, Biopartners and Sanofi-Aventis.

Maria Trojano - Declared receipt of research support from Biogen Idec, Merck Serono, Sanofi-Aventis and Bayer Schering.

Robert Weissert - Declared to be employed at the Geneva Research Institute, Merck Serono International S.A., since February 2007.

Frauke Zipp - Declared research support from Bayer Schering Pharma and Teva.