Tuesday November 16

15.00 Welcome and Introduction
Dr. A. Belgorosky (Argentina), Dr M.A.Rivarola (Argentina)

SESSION 1

THE ERA OF GENOMICS IN HUMAN ADRENARCHE AND PUBERTY
Coordinators: C. Libertun (Argentina) and J. J. Heinrich (Argentina)

15.15 Pediatric Research in the Era of Genomics
O. Pescovitz (USA)

16.00 Estrogen receptors and endocrine diseases. Lessons from estrogen receptor knock out mice
K. Korach (USA)

16.45 Genetic Approaches to Unraveling Reproduction Disorders in the Genomic Era
S. Seminara (USA)

Wednesday, November 17

SESSION 2

ADRENAL DIFFERENTIATION AND GROWTH
Coordinators: B. Mendonça (Brasil) and S. Cigorraga (Argentina)

8.30 Transcription Factors in Adrenocortical Growth and Steroidogenesis
C. L. Coulter (Australia)

9.15 Adrenarche: Molecular Basis
W. Miller (USA)

10.00 Nitric Oxide synthetase and tyrosine phosphatases in adrenal gland
E. Podesta (Argentina)

10.45 Coffee Break

SESSION 3

FAT MASS, INSULIN SENSITIVITY AND THE GH-IGF AXIS ON ADRENAL ANDROGENS
Coordinators: V. Merick (Chile) and A. Martínez (Argentina)

11.15 GH-IGF-1 Axis and Insulin Sensitivity in Human Adrenarche.
A.Belgorosky (Argentina)

12.00 Insulin Sensitivity and THE Insulin -Like Growth FACTOR system in Premature Adrenarche in Prepubertal Boys and Girls.
S. Oberfield (USA)

12.45 Lunch

SESSION 4

THE NEUROENDOCRINOLOGY OF HUMAN PUBERTY
Coordinators: M. Barontini (Argentina) and C. Longhi (Brasil)

15.00 Glia-to-Neuron Signaling and the Neuroendocrine Control of Puberty
S. Ojeda (USA)

15.45 Gonadotropin-releasing hormone gene expression; In Vitro and In Vivo studies.
S. Radovick(USA)

16:30 Coffee Break

Coordinators: F. Cassorla (Chile) and M. Ciaccio (Argentina)

17:00 Brain Sexual Differentiation and Gonadotropins Secretion in the Rat
D. Becu-Villalobos (Argentina)

17:45 Sex Steroids in the Regulation of Pituitary Gonadotropin Isoforms
S. Campo (Argentina)

Thursday November 18

SESSION 5

PUBERTAL DISORDERS (1)
Coordinators: H. Fideleff (Argentina) and M. Miras (Argentina)

9.30 Estrogen receptor null mice and the hypothalamic-pituitary-gonadal axis
K. Korach (USA)

10.15 Role of Inhibin in Childhood and Puberty
I. Bergada (Argentina)

11:00 Coffee Break

Coordinators: T. Pasqualini (Argentina) and R. Sandrini (Brasil)

11:30 Phenotipic Spectrum of Idiopathic Hypogonadotropic Hypogonadism
S. Seminara (USA)

12:15 Pubertal characteristics of androgen insensitivity syndrome.
I. Arnhold (Brazil)

13:00 Lunch

PUBERTAL DISORDERS (2)
Coordinators: M. E. Escobar (Argentina) and R. Calzada (Mexico)

14.30 Treatment of Precocious Puberty
O. Pescovitz (USA)

15.15 Intracrinology of the adipose tissue
Z. Hochberg (Israel)

Coordinators: M. Warman (Argentina) and E. Berensztein (Argentina)

16.00 Conclusions and remarks
S. Malozowski (USA)